Can drug abuse cause parkinson's?

Asked By: Anya Goodwin
Date created: Fri, Feb 26, 2021 6:56 PM
Best answers
During the last few years, a possible specific cause triggering death of dopaminergic neurons in the substantia nigra, drug of abuse-induced neurotoxicity, is being considered as a potential mechanism to develop PD, especially in the case of abuse of amphetamine and its derivatives.
Answered By: Felipa Larkin
Date created: Sat, Feb 27, 2021 8:59 PM

Researchers unveil drug that slows and treats parkinson’s disease

Researchers unveil drug that slows and treats parkinson’s disease
During the last few years, a possible specific cause triggering death of dopaminergic neurons in the substantia nigra, drug of abuse-induced neurotoxicity, is being considered as a potential mechanism to develop PD, especially in the case of abuse of amphetamine and its derivatives.
Answered By: Genoveva Kub
Date created: Mon, Mar 1, 2021 1:27 AM
Recently, a street-drug contaminant has appeared that can cause parkinsonism in drug abusers. The compound N-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) has been identified in underground laboratory preparations of a potent analog of meperidine (Demerol).
Answered By: Stefan Berge
Date created: Tue, Mar 2, 2021 1:56 AM
The National Institute on Drug Abuse reports that methamphetamine and amphetamine abuse can increase the risk of developing Parkinson’s disease. A main insight from this research is that abuse of these types of drugs damages dopamine neurons in the brain.
Answered By: Wava Fay
Date created: Thu, Mar 4, 2021 12:13 AM
A number of medications can cause parkinsonism because they block the dopamine receptor and thereby mimic the symptoms of PD that are caused by loss of dopamine neurons in the brain. Reviewing a patient’s medications is therefore a critical step for a neurologist when seeing someone with parkinsonism.
Answered By: Coby Jaskolski
Date created: Fri, Mar 5, 2021 12:12 PM
While amphetamine/methamphetamine and cocaine have shown to be associated with PD; others such as alcohol and smoking have either not been associated or are considered as possibly neuroprotective against PD.
Answered By: Astrid Swaniawski
Date created: Sat, Mar 6, 2021 12:56 AM
Drug-induced parkinsonism (DIP) is the second-most-common etiology of parkinsonism in the elderly after Parkinson's disease (PD). Many patients with DIP may be misdiagnosed with PD because the clinical features of these two conditions are indistinguishable.
Answered By: Grayson Deckow
Date created: Mon, Mar 8, 2021 11:14 AM
Adults who abuse cocaine might increase their risk of developing Parkinson's disease (PD), and pregnant women who abuse cocaine could increase the risk of their children developing PD later in...
Answered By: Toby Koelpin
Date created: Wed, Mar 10, 2021 5:19 AM
Any drug that blocks the action of dopamine (referred to as a dopamine antagonist) is likely to cause parkinsonism. Drugs used to treat schizophrenia and other psychotic disorders such as behaviour disturbances in people with dementia (known as neuroleptic drugs) are possibly the major cause of drug-induced parkinsonism worldwide. Parkinsonism can occur from the use of any of the various classes of neuroleptics (see Table 1 at the end of this information sheet).
Answered By: Luis Gibson
Date created: Wed, Mar 10, 2021 12:29 PM
Parkinson's from all clinical knowledge is genetic although there may be some other factors. That much is under research. Parkinsonism (which is separate from Parkinson's in that it is induced artificially) can be induced by a variety of illegal drugs such as amphetamines.
Answered By: Braden Cronin
Date created: Thu, Mar 11, 2021 5:24 AM
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