Can drug use cause pemphigus vulgaris?

Asked By: Zaria Connelly
Date created: Mon, Mar 1, 2021 6:58 PM
Best answers
Drugs that induce pemphigus may be categorized into 2 groups: thiol drugs and nonthiol drugs. Thiol drugs are reported most frequently as the culprits of drug-induced pemphigus.
Answered By: Riley Schmitt
Date created: Tue, Mar 2, 2021 9:01 PM

Drug-induced pemphigus

Drug-induced pemphigus
While the disease is likely multifactorial, drug-induced pemphigus is the most common cause. Pemphigus vulgaris is the most common variant, with an incidence as high as 0.1 to 0.5 per 100,000 people. Pemphigus vulgaris also has a higher incidence among the Jewish population and in those individuals of Mediterranean descent.
Answered By: Estelle Schumm
Date created: Fri, Mar 5, 2021 12:36 AM
Drugs are a leading cause of pemphigus. There is a need for a thorough history taking so as to find the culprit medication. The diagnosis of drug-induced pemphigus is challenging. Patients have often been exposed to multiple drugs, and some drugs may have a prolonged latency period between exposure and onset of the disease.
Answered By: Keeley Mueller
Date created: Fri, Mar 5, 2021 10:52 PM
Pemphigus is an autoimmune bullous disease characterized by blisters and erosions of the skin and mucous membranes. Several variants of the disease exist, including pemphigus vulgaris, pemphigus foliaceous, and drug-induced pemphigus. Patients with drug-induced pemphigus have autoantibodies that are either circulating or tissue bound.
Answered By: Janis Pouros
Date created: Sun, Mar 7, 2021 9:09 PM
Causes of Drug-Induced Pemphigus. D-Penicillamine (5% Incidence with Penicillamine) Captopril. IV. Signs of Drug-Induced Pemphigus. Pemphigus follows medication use of >2 month duration. Similar to Superficial Pemphigus ( Pemphigus Foliaceus) Most cases are mild.
Answered By: Edward McLaughlin
Date created: Tue, Mar 9, 2021 5:29 PM
There are few drugs that can induce pemphigus vulgaris, which are angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, cephalosporins and penicillamine. However, this is a very rare cause and this disease is more common in Jews and Middle Eastern due to some genetic factors.
Answered By: Hobart Senger
Date created: Thu, Mar 11, 2021 11:36 PM
Pemphigoid diseases are a group of blistering autoimmune pathologies including pemphigus vulgaris (PV) and pemphigus foliaceous, which affect mucocutaneous tissues. Non-steroidal anti-inflammatory drugs, penicillamine, and angiotensin-converting enzyme inhibitors such as captopril and enalapril are associated with drug-induced pemphigoid.
Answered By: Alvah Wolff
Date created: Fri, Mar 12, 2021 11:38 PM
PV used to be an indefinitely fatal disease before the introduction of corticosteroids as the primary form of treatment. The main treatment for PV includes systemic corticosteroids and immunosuppressive agents, but due to adverse reactions and therapeutic failure, new drugs such as rituximab and mycophenolate mofetil have been used.
Answered By: Albin Mayer
Date created: Mon, Mar 15, 2021 4:07 AM
The effect of many of the drugs used for treatment of Pemphigus vulgaris (PV) on COVID-19 is not clear. We also do not have data on the impact of this autoimmune disease, which may involve the mucous membranes, on the acquisition or course of COVID-19.
Answered By: Caleigh Koch
Date created: Wed, Mar 17, 2021 9:58 AM
Drugs that cause pemphigus include: Thiol drugs, including penicillamine, captopril. Antibiotics: penicillins, cephalosporins, vancomycin. Antihypertensive drugs: other angiotensin-converting enzyme inhibitors such as cilazapril, lisinopril, enalapril.
Answered By: Aaron Berge
Date created: Fri, Mar 19, 2021 11:49 AM
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