How does chemotherapy drugs affect cancer cells?

Lulu Zemlak asked a question: How does chemotherapy drugs affect cancer cells?
Asked By: Lulu Zemlak
Date created: Thu, Mar 4, 2021 10:02 AM

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Those who are looking for an answer to the question «How does chemotherapy drugs affect cancer cells?» often ask the following questions:

❔ What does chemotherapy drugs affect in cancer cells?

Usually, cancer drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division. If the cancer cells are unable to divide, they die. The faster that cancer cells divide, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink.

❔ How do chemotherapy drugs affect cancer cells?

Usually, cancer drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division. If the cancer cells are unable to divide, they die. The faster that cancer cells divide, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink.

Question from categories: drug resistance

❔ Can chemotherapy drugs kill cancer cells?

First, conventional chemotherapy drugs such as paclitaxel mainly target proliferating cancer cells. Such drugs kill the majority of proliferating cancer cells, but cannot do so with dormant cancer cells, which can divide into proliferating cancer cells and cause relapses following chemotherapy [1,2].

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Chemotherapy drugs act not only on cancer cells but on normal cells as well, accounting for many of the side effects—such as hair loss and nausea, and increased susceptibility to infection—commonly associated with the drugs. Normal cells are better able to recover from chemotherapy because the drugs have a disproportionate impact on cells whose growth-control systems have broken down—that is, cancer cells.

However, chemo drugs can’t tell the difference between healthy cells and cancer cells. This means normal cells are damaged along with the cancer cells, and this causes side effects. Each time chemo is given, it means trying to find a balance between killing the cancer cells (in order to cure or control the disease) and sparing the normal cells (to lessen side effects).

Chemotherapy drugs either interfere with the process of DNA replication, or directly damage the DNA so badly the cell must go through apoptosis, killing the cancer cells. However, chemotherapy...

First, conventional chemotherapy drugs such as paclitaxel mainly target proliferating cancer cells. Such drugs kill the majority of proliferating cancer cells, but cannot do so with dormant cancer cells, which can divide into proliferating cancer cells and cause relapses following chemotherapy [1,2].

Chemotherapy can kill cancer cells by inhibiting the cell division process. The drugs given during chemotherapy work by damaging the DNA or the RNA that make the cell divide. When these cells do not divide, they ultimately die. This treatment also induces self-death or cell suicide.

Chemotherapy drugs kill cancer cells, but they can also damage healthy cells. Damage to healthy cells causes side effects. Different cells and tissues in the body cope differently with chemotherapy.

Because cancer cells divide much more often than most normal cells, chemotherapy is much more likely to kill them. Some drugs kill dividing cells by damaging the part of the cell's control centre that makes it divide. Other drugs interrupt the chemical processes involved in cell division. The effects on dividing cells

The ability of chemotherapy to kill cancer cells depends on its ability to halt cell division. Usually, cancer drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division. If the cancer cells are unable to divide, they die. The faster that cancer cells divide, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink. They also induce cell suicide (self-death or apoptosis).

These cells can grow new tumors or spread the cancer to other parts of your body. Chemotherapy drugs help destroy, shrink, or control those cells. It might also treat symptoms the cancer causes,...

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